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Neuropediatrics 1996; 27(1): 42-44
DOI: 10.1055/s-2007-973746
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© Hippokrates Verlag GmbH Stuttgart

Successful Treatment of Transverse Myelitis in a Child with Systemic Lupus Erythematosus

By V. Baca1 , G. Sanchez-Vaca2 , Irma Martínez-Muñiz3 , Martha Ramírez-Lacayo1 , C. Lavalle1
  • 1Departments of Rheumatology Hospital de Pediatría, Centra Médico Nacional Siglo XXI, Institute Méxicano del Seguro Social, México, D.E
  • 2Departments of Neurology Hospital de Pediatría, Centra Médico Nacional Siglo XXI, Institute Méxicano del Seguro Social, México, D.E
  • 3Departments of Radiology, Hospital de Pediatría, Centra Médico Nacional Siglo XXI, Institute Méxicano del Seguro Social, México, D.E
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Publication History

Publication Date:
13 March 2007 (online)

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Abstract

We describe a 13-year-old female patient with systemic lupus erythematosus (SLE) who presented with acute transverse myelitis (ATM) in the course of SLE. IgG and IgM anticardioljpin antibodies (aCL) were positive at moderate titers. Magnetic resonance imaging (MRI) of the. thoracic spine demonstrated decreased signal intensity and diffuse edema of the spinal cord from T2 to T6 on T1 weighted images. Dramatic clinical improvement of the neurologic impairment was noted a few days after high dose intravenous (IV) methylprednisolone (MP) and cyclophosphamide (Cy). Herein we further emphasize the benefit of IV MP and Cy in ATM and the relationship between ATM and antiphospholipid antibodies (aPLA) in SLE.

Key words

Transverse myelitis - SLE - Antiphospholipid antibodies

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