Allergie und Parasiten

Schlüsselwörter

Allergie - Typ 2 Immunität - Helminthparasiten - Regulatorische T-Zellen - Alternativ aktivierte Makrophagen

Key words

allergy - type 2 immunity - helminth parasites - regulatory T cells - alternatively activated macrophages

Literatur

• 1 Bach J F. The effect of infections on susceptibility to autoimmune and allergic diseases.  N Engl J Med. 2002;  347 911-920
• 2 Brockschnieder D, Lappe-Siefke C, Goebbels S. et al . Cell depletion due to diphtheria toxin fragment A after Cre-mediated recombination.  Mol Cell Biol. 2004;  24 7636-7642
• 3 Elston D M. The hygiene hypothesis and atopy: bring back the parasites?.  J Am Acad Dermatol. 2006;  54 172-179
• 4 Humbles A A, Loyd C M, McMillan S J. et al . A critical role for eosinophils in allergic airways remodeling.  Science. 2004;  305 1776-1779
• 5 Lee J J, Dimina D, Macias M P. et al . Defining a link with asthma in mice congenitally deficient in eosinophils.  Science. 2004;  305 1773-1776
• 6 Maizels R M, Yazdanbakhsh M. Immune regulation by helminth parasites: cellular and molecular mechanisms.  Nat Rev Immunol. 2003;  3 733-744
• 7 Mohrs M, Shinkai K, Mohrs K, Locksley R M. Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter.  Immunity. 2001;  15 303-311
• 8 Summers R W, Elliott D E, Urban J F, Thompson R, Weinstock J V. Trichuris suis therapy in Crohn’s disease.  Gut. 2005;  54 87-90
• 9 Voehringer D, Shinkai K, Locklsey R M. Type 2 immunity reflects orchestrated recruitment of cells committed to IL-4 production.  Immunity. 2004;  20 267-277