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psychoneuro 2007; 33(4): 143-148
DOI: 10.1055/s-2007-981702
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© Georg Thieme Verlag Stuttgart · New York

Geschlechtseffekte und Bildgebung - Strukturelle und funktionelle Unterschiede

Gender specific differences and imagingDieter F. Braus1 , 2 , Jan F. Lehmbeck2 , Stefanie Brassen2
  • 1Klinik und Poliklinik für Psychiatrie und Psychotherapie, HSK, Dr.-Horst-Schmidt-Klinik Wiesbaden (Direktor: Prof. Dr. Dieter F. Braus)
  • 2NeuroImage Nord, Psychiatrie, Universitätsklinikum Hamburg-Eppendorf (UKE)
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Publication History

Publication Date:
06 June 2007 (online)

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Gewisse Unterschiede zwischen den Geschlechtern im Verhalten, der Interaktion und in seelischen Funktionen sind im Alltag sichtbar, die Forschung widmet sich den dafür verantwortlichen neuronalen Korrelaten jedoch erst seit kurzem. Besonders bei der geschlechtsspezifischen Betrachtung seelischer Störungen kommt den Unterschieden und Gemeinsamkeiten biologischer Prozesse jedoch eine besondere Bedeutung zu. Die moderne Bildgebung kann mittelfristig einen relevanten Beitrag zur Aufklärung der unterschiedlichen Ebenen der Hirnfunktion und -struktur leisten. Der folgende Artikel fasst den derzeitigen Stand über Geschlechtseffekt und Bildgebung mit besonderem Augenmerk auf Probandenstudien, bei Schizophrenien sowie affektiven Störungen kritisch zusammen.

Gender specific differences in behaviors, interaction and mental functions are evident in everyday life; research, however, has attended to the related responsible neuronal correlates for a short time only. Differences and similarities of biological processes are of particular importance, especially in the gender specific observation of mental disorders. In the medium term modern imaging methods may contribute essentially to elucidation in different levels of function and structure of the brain. The following paper summarizes critically the present level of gender effect and imaging, especially concerning healthy subject trials and schizophrenia as well as affective disorders.

Key words

gender effect - imaging - MRI - schizophrenia - affective disorder

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Korrespondenz

Prof. Dr. Dieter F. Braus

Direktor der Klinik und Poliklinik für Psychiatrie und Psychotherapie, HSK, Dr.-Horst-Schmidt-Klinik

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65199 Wiesbaden

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