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DOI: 10.1055/s-2007-996213
Correlations between Adenohypophyseal Weight, Serum Polyphenol Oxidase Activity (Ceruloplasmin) and Hypothalamic Ascorbic Acid after Estrogen Treatment in Rats
Publication History
1979
1979
Publication Date:
14 March 2008 (online)
Summary
Serum polyphenol oxidase activity (ceruloplasmin) and the hypothalamic ascorbic acid concentration were determined in control rats and rats given estradiol for 2-6 months. A significant positive correlation (r = 0.5948, p < 0.01) was found between adenohypophyseal weight and the ceruloplasmin level and a negative correlation between adenohypophyseal weight and the ascorbic acid concentration in the hypothalamus (r = -0.5728, p < 0.01) and between the hypothalamus ascorbic acid concentration and the ceruloplasmin level (r = -0.7059, p < 0.01). The ways in which an increase in serum polyphenol oxidase activity might modulate the adenohypophyseal reaction to estradiol are discussed.
Key-Words
Adenohypophysis - Estradiol - Growth - Ceruloplasmin - Hypothalamic Ascorbic Acid