Sonoelastographically Guided Preoperative Localization of Suspicious Breast Microcalcifications Detected with Mammography

Introduction

Most breast cancers are stiffer than surrounding normal breast parenchyma, mainly due to the accompanying desmoplastic reaction of the affected tissue (Martegani A et al. ECR 2005; C-0209). The principle of sonoelastography relies on the relative resistance of stiff tissues to movement compared to softer adjacent ones when slight probe pressure is applied (Itoh A et al. Radiology 2006; 239: 341 – 350).

Although the majority of microcalcifications are preoperatively localized by stereotactic or mammographic means, ultrasound-guided procedures are preferred whenever possible due to their relative ease-of-use and speed which appeal both to patients and physicians. Breast elastography has mainly focused in recent years on circumscribed, solid, and cystic lesions, while the case reported here focuses on a non-nodular abnormality (Hatzung G et al. Ultraschall in Med 2008; 29; Duma M et al. Ultraschall in Med 2008; 29).