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Neuropediatrics 1989; 20(4): 211-214
DOI: 10.1055/s-2008-1071295
Original article

© Georg Thieme Verlag KG Stuttgart · New York

Ultrasonographical and Morphological Examination of Subependymal Cystic Lesions in Maturely Born Infants

T.  Mito1,3 , Y.  Ando1 , K.  Takeshita1 , K.  Takada2 , S.  Takashima3
  • 1Division of Child Neurology, Institute of Neurological Sciences, Tottori University School of Medicine, Japan
  • 2Division of Neuropathology, Institute of Neurological Sciences, Tottori University School of Medicine, Japan
  • 3Division of Mental Retardation and Birth Defect Research, National Institute of Neuroscience, NCNP, Japan
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Publication History

Publication Date:
19 March 2008 (online)

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Abstract

The clinical data and development of 8 cases with subependymal cysts detected on neurosonography in the neonatal period were studied, and the prognosis was found to vary. Also, clinico-pathological examination of 15 autopsied cases of congenital subependymal cysts (SEC) was performed, with immunohistochemical staining involving neuron-specific enolase in three cases, which revealed that congenital SEC are often complicated by various degrees of brain and heart anomalies, and suggested that SEC might occur in a wide gestational age range, with various causes. Therefore, it is important in the future to determine the agents which cause destruction of the subependymal germinal matrix.

Key words

Subependymal cysts - Subependymal hemorrhage - Subependymal germinolysis - Ultrasonography

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