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Neuropediatrics 1992; 23(4): 192-195
DOI: 10.1055/s-2008-1071339
Original article

© Georg Thieme Verlag KG Stuttgart · New York

The Natural History of Acute Disseminated Leukoencephalitis. A Serial Magnetic Resonance Imaging Study

S.  Kimura1 , T.  Unayama2 , T.  Mori2
  • 1Department of Pediatrics, Yokohama City University School of Medicine
  • 2Division of Pediatrics, Saiseikai Yokohamashi Nanbu Hospital, Yokohama, Japan
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Publication History

Publication Date:
19 March 2008 (online)

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Abstract

The natural history of acute disseminated (leuko)encephalitis (ADE) in a 3-year-old girl who did not receive steroid therapy is reported. Serial MR studies disclosed: 1) white matter lesions resolved spontaneously, though very slowly, 2) active disease persisted for around three months and coincided with the onset of new subcortical lesions. These subcortical lesions were associated with hyperactivity, suggesting a possible etiologic correlation.

Key words

Acute disseminated encephalitis - ADEM - MR

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