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Thromb Haemost 2005; 94(01): 26-36
DOI: 10.1160/TH04-12-0818
Review Article
Schattauer GmbH

Ultrasound thrombolysis

Stefan Pfaffenberger
1   Department of Internal Medicine II, University of Vienna, Austria
,
Branka Devcic-Kuhar
2   Institute of General Physics, Vienna University of Technology, Austria
,
Stefan P. Kastl
1   Department of Internal Medicine II, University of Vienna, Austria
,
Kurt Huber
3   3rd Department of Medicine (Cardiology and Emergency Medicine), Wilhelminenspital, Vienna, Austria
,
Gerald Maurer
1   Department of Internal Medicine II, University of Vienna, Austria
,
Johann Wojta
1   Department of Internal Medicine II, University of Vienna, Austria
,
Michael Gottsauner-Wolf
1   Department of Internal Medicine II, University of Vienna, Austria
› Author Affiliations
Further Information

Publication History

Received 18 December 2004

Accepted after resubmission 09 April 2005

Publication Date:
05 December 2017 (online)

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Summary

Cardiovascular diseases are a major cause of mortality in the developed world. Efficacy of thrombolysis plays an important role in the management of acute myocardial infarction and cerebral insult both in the acute event and in the long-term outcome of these patients. New adjunctive strategies have been tested, therefore, to make thrombolytic therapies more effective and safer. Ultrasound Thrombolysis is a technique which showed promising results under in vitro conditions and in animal studies. Now clinical trials have to prove if it is also feasible for clinical application. This report gives an overview on different technical approaches and their current performances in the clinical setting. All original articles are chronologically ordered in tables providing detailed information on each study concerning experimental design, acoustical parameters and thrombolysis outcome.

Keywords

Ultrasound - thrombolysis - adjunctive therapy - myocardial infarction - stroke - sonothrombolysis
 

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