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Thromb Haemost 2011; 106(05): 990-992
DOI: 10.1160/TH11-04-0277
Letters to the Editor
Schattauer GmbH

Interference of rivaroxaban in one-stage and chromogenic factor VIII:C assays

Vladimir Tichelaar
1   Division of Haemostasis and Thrombosis, Department of Haematology, University Medical Centre Groningen, Groningen, the Netherlands
,
Helma de Jong
2   Department of Laboratory Medicine, University Medical Centre Groningen, Groningen, the Netherlands
,
Hendrik Nijland
2   Department of Laboratory Medicine, University Medical Centre Groningen, Groningen, the Netherlands
,
Hanneke Kluin-Nelemans
1   Division of Haemostasis and Thrombosis, Department of Haematology, University Medical Centre Groningen, Groningen, the Netherlands
,
Karina Meijer
1   Division of Haemostasis and Thrombosis, Department of Haematology, University Medical Centre Groningen, Groningen, the Netherlands
,
André Mulder
2   Department of Laboratory Medicine, University Medical Centre Groningen, Groningen, the Netherlands
› Author Affiliations
Further Information

Publication History

Received: 28 April 2011

Accepted after major revision: 09 August 2011

Publication Date:
23 November 2017 (online)

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  • References

  • 1 Eriksson BI, Quinlan DJ. Oral anticoagulants in development- Focus on thromboprophylaxis in patients undergoing orthopedic surgery. Drugs 2006; 66: 1411-1429.
    CrossrefPubMedGoogle Scholar
  • 2 Mueck W, Borris LC, Dahl OE. et al. Population pharmacokinetics and pharmacodynamics of once- and twice-daily rivaroxaban for the prevention of venous thromboembolism in patients undergoing total hip replacement. Thromb Haemost 2008; 100: 453-461.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 3 Laux V, Perzborn E, Heitmeier S. et al. Direct inhibitors of coagulation proteins - the end of the heparin and low-molecular-weight heparin era for anticoagulant therapy?. Thromb Haemost 2009; 102: 892-899.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 4 Ufer M. Comparative efficacy and safety of the novel oral anticoagulants dabigatran, rivaroxaban and apixaban in preclinical and clinical development. Thromb Haemost 2010; 103: 572-585.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 5 Ahrens I, Lip GY, Peter K. New oral anticoagulant drugs in cardiovascular disease. Thromb Haemost 2010; 104: 49-60.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 6 Samama MM, Martinoli JL, LeFlem L. et al. Assessment of laboratory assays to measure rivaroxaban - an oral, direct factor Xa inhibitor. Thromb Haemost 2010; 103: 815-825.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 7 Jiang J, Hu Y, Zhang J. et al. Safety, pharmacokinetics and pharmacodynamics of single doses of rivaroxaban - an oral, direct factor Xa inhibitor - in elderly Chinese subjects. Thromb Haemost 2010; 103: 234-241.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 8 Merriman E, Kaplan Z, Butler J. et al. Rivaroxaban and false positive lupus anticoagulant testing. Thromb Haemost 2011; 105: 385-386.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 9 Mani H, Hesse C, Stratmann G. et al. Rivaroxaban differentially influences ex vivo global coagulation assays based on the administration time. Thromb Haemost 2011; 106: 156-164.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 10 The EINSTEIN Investigators Oral rivaroxaban for symptomatic venous thromboembolism. N Engl J Med 2010; 363: 2499-2510.
    CrossrefPubMedGoogle Scholar
  • 11 Hillarp A, Baghaei F, Fagerberg Blixter I. et al. Effects of the oral, direct factor Xa inhibitor rivaroxaban on commonly used coagulation assays. J Thromb Haemost 2011; 9: 133-139.
    CrossrefPubMedGoogle Scholar
  • 12 O'Donnell J, Tuddenham EG, Manning R. et al. High prevalence of elevated factor VIII levels in patients referred for thrombophilia screening: role of increased synthesis and relationship to the acute phase reaction. Thromb Haemost 1997; 77: 825-828.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 13 Berger M, Mattheisen M, Kulle B. et al. High factor VIII levels in venous thromboembolism show linkage to imprinted loci on chromosomes 5 and 11. Blood 2005; 105: 638-644.
    CrossrefPubMedGoogle Scholar
  • 14 O'Donnell J, Mumford AD, Manning RA. et al. Elevation of FVIII: C in venous thromboembolism is persistent and independent of the acute phase response. Thromb Haemost 2000; 83: 10-13.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 15 Kamphuisen PW, Eikenboom JC, Vos HL. et al. Increased levels of factor VIII and fibrinogen in patients with venous thrombosis are not caused by acute phase reactions. Thromb Haemost 1999; 81: 680-683.
    Article in Thieme ConnectPubMedGoogle Scholar
  • 16 Mismetti P, Laporte S. New oral antithrombotics: a need for laboratory monitoring. For. J Thromb Haemost 2010; 8: 621-626.
    CrossrefPubMedGoogle Scholar