Luteolin, an abundant dietary component is a potent anti-leishmanial agent that acts by inducing topoisomerase II-mediated kinetoplast DNA cleavage leading to apoptosis - Mittra, B; Saha, A; Chowdhury, A R; Pal, C; Mandal, S; Mukhopadhyay, S; Bandyopadhyay, S; Majumder, H K (Mol Med, 2000)