Atypical PKC, PKCλ/ι, activates β-secretase and increases Aβ1–40/42 and phospho-tau in mouse brain and isolated neuronal cells, and may link hyperinsulinemia and other aPKC activators to development of pathological and memory abnormalities in Alzheimerʼs disease - Sajan, M P; Hansen, B C; Higgs, M G; Kahn, C R; Braun, U; Leitges, M; Park, C R; Diamond, D M; Farese, R V (Neurobiol Aging, 2018)