Topical recombinant thrombin at a concentration of 1000 IU/mL reliably shortens in vivo TTH and delivers durable hemostasis in the presence of heparin anticoagulation and clopidogrel platelet inhibition in a rabbit model of vascular bleeding - Hughes,S.D.; Bishop,P.D.; Garcia,R.; Zhang,T.; Alexander,W.A. (Ann Surg Innov Res, 2009)