One-year increase of Coll 2–1, a new marker of type II collagen degradation, in urine is highly predictive of radiological OA progression - Deberg,M.A.; Labasse,A.H.; Collette,J.; Seidel,L.; Reginster,J.Y.; Henrotin,Y.E. (Osteoarthritis Cartilage, 2005)