TY - JOUR AU - Chu, Lingling; Qing, Feng-Ling TI - Copper-Catalyzed Aerobic Oxidative Trifluoromethylation of H-Phospho­nates Using Trimethyl(trifluoromethyl)silane SN - 0039-7881 SN - 1437-210X PY - 2012 JO - Synthesis JF - Synthesis LA - EN VL - 44 IS - 10 SP - 1521 EP - 1525 ET - 2012/04/11 DA - 2012/05/07 KW - copper catalysis KW - phosphonates KW - trifluoromethylation AB - Copper-catalyzed aerobic oxidative trifluoromethylation of readily accessible H-phosphonates was demonstrated for the first time. This method not only provides an alternative method for the facile synthesis of a series of biologically important CF3-phosphonates, but also demonstrates the first example of the efficient construction of a P–CF3 bond via transition-metal catalysis. PB - © Georg Thieme Verlag DO - 10.1055/s-0031-1290806 UR - http://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0031-1290806 ER -