The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and plays an integral role in insulin signal transduction - Mahadev, K; Motoshima, H; Wu, X; Ruddy, J M; Arnold, R S; Cheng, G; Lambeth, J D; Goldstein, B J (Mol Cell Biol, 2004)