TY - JOUR AU - Phung, Thuy L.; Hochman, Marcelo TI - Pathogenesis of Infantile Hemangioma SN - 0736-6825 SN - 1098-8793 PY - 2012 JO - Facial Plast Surg JF - Facial Plastic Surgery LA - EN VL - 28 IS - 06 SP - 554 EP - 562 DA - 2012/11/27 KW - infantile hemangioma KW - pathogenesis KW - vascular anomalies KW - vascular tumors AB - Cutaneous vascular anomalies are congenital disorders of abnormal vascular development and growth. Infantile hemangioma is a common type of vascular anomalies characterized by the abnormal growth of blood vessels in the early proliferative phase, followed by the gradual spontaneous regression of the lesion in the involuting phase. Over the past decade, significant advances have been made in our understanding of the cellular and molecular mechanisms that control the development, growth, and regression of infantile hemangioma. In this article, we present a comprehensive review of the current knowledge of the pathogenesis of hemangioma as well as promising research horizons and implications for new therapeutic advances. PB - Thieme Medical Publishers DO - 10.1055/s-0032-1329930 UR - http://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0032-1329930 ER -