TY - JOUR AU - Hu, Xiao-Si; Du, Yi; Yu, Jin-Sheng; Liao, Fu-Min; Ding, Pei-Gang; Zhou, Jian TI - A Highly Efficient Gold(I)-Catalyzed Mukaiyama–Mannich Reaction of α-Amino Sulfones with Fluorinated Silyl Enol Ethers To Give β-Amino α-Fluorinated Ketones SN - 0936-5214 SN - 1437-2096 PY - 2017 JO - Synlett JF - Synlett LA - EN VL - 28 IS - 16 SP - 2194 EP - 2198 ET - 2017/07/12 DA - 2017/09/18 KW - Mukaiyama–Mannich reaction KW - fluorinated silyl enol ethers KW - amino sulfones KW - amino fluorinated ketones KW - gold catalysis AB - Ph3PAuOTf was identified as a powerful catalyst for the ­Mukaiyama–Mannich reaction of fluorinated silyl enol ethers with α-amino sulfones. This provides ready access to β-amino α-fluorinated ketones in good to excellent yields. PB - © Georg Thieme Verlag DO - 10.1055/s-0036-1588475 UR - http://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0036-1588475 ER -