TY - JOUR AU - Wei, Wen-Ting; Ying, Wei-Wei; Zhu, Wen-Ming; Wu, Yi; Huang, Yi-Ling; Cao, Yi-Qi; Wang, Yi-Ning; Liang, Hongze TI - Convenient and Clean Synthesis of Isatins by Metal-Free Oxidation of Oxindoles SN - 0936-5214 SN - 1437-2096 PY - 2017 JO - Synlett JF - Synlett LA - EN VL - 28 IS - 17 SP - 2307 EP - 2310 ET - 2017/07/21 DA - 2017/10/10 KW - oxidation KW - oxindoles KW - butyl nitrite KW - isatins KW - metal-free synthesis AB - A metal-free synthesis of isatins was achieved through the oxidative reactions of oxindoles with molecular oxygen in the presence of tert-butyl nitrite as an additive. This strategy provides a convenient and simple synthetic route to the construction of C=O bonds without the need for any catalyst or base. The attractive features of this reaction include its convenient procedure and mild reaction conditions. PB - © Georg Thieme Verlag DO - 10.1055/s-0036-1590965 UR - http://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0036-1590965 ER -