TY - JOUR AU - Potuganti, Gal Reddy; Indukuri, Divakar Reddy; Alla, Manjula TI - An Efficient One-Pot Multicomponent Synthesis of Tetracyclic Quinazolino[4,3-b]quinazolines by Sequential C–N Bond Formation and Copper-Mediated Aerobic Oxidative Cyclization SN - 0936-5214 SN - 1437-2096 PY - 2018 JO - Synlett JF - Synlett LA - EN VL - 29 IS - 13 SP - 1717 EP - 1722 ET - 2018/05/04 DA - 2018/08/01 KW - quinazolinoquinazoline KW - copper catalysis KW - oxidative cyclization KW - C–N bond formation. AB - An efficient one-pot synthesis of quinazolino[4,3-b]quinazoline derivatives has been accomplished, starting from 2-(2-bromo­phenyl)quinazolin-4(3H)-one, aldehydes, and various nitrogen sources under aerobic conditions. The multicomponent protocol is mediated by copper(I) salts and involves amination of 2-(2-bromophenyl)quinazolin-4(3H)-one, followed by condensation with the aldehyde and an oxidative cyclization to give the target compounds in moderate to good yields. PB - © Georg Thieme Verlag DO - 10.1055/s-0036-1591578 UR - http://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0036-1591578 ER -