TY - JOUR AU - Araújo Júnior, Antonio Santos de; Arlant, Pedro Alberto; Salvestrini Júnior, Arnaldo; Fernandez, Angelo; Docema, Marcos Fernando de Lima; Mattedi, Rômulo Loss; Silveira, Thales Parenti; Caldas, José Guilherme Mendes Pereira; Fazzito, Mirella Martins TI - Low-grade Endometrial Stromal Sarcoma with Unusual Metastasis to the Skull TT - Sarcoma endometrial estromal de baixo grau com metástase incomum no crânio SN - 0103-5355 SN - 2359-5922 PY - 2018 JF - Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery LA - EN VL - 37 IS - 01 SP - 42 EP - 46 ET - 2017/12/15 DA - 2018/04/13 KW - endometrial stromal sarcoma KW - lung and skull metastases AB - Background Endometrial stromal sarcomas (ESSs) are the second most common uterine sarcomas. Although ESSs are often indolent, they have metastatic potential. To the best of our knowledge, there are only three reports of brain metastasis, and the present report is the first to describe a late skull metastasis of an ESS.Case Report We describe the case of a 51-year-old woman who presented abnormal vaginal bleeding 14 years ago; she was diagnosed with an uterine mass and submitted to a hysterectomy. One year ago she presented ESS lung metastasis followed by a left parietal calvarial metastasis. The optimal treatment for metastatic ESS is controversial, but the use of progesterone and aromatase inhibitors is advisable. PB - Thieme Revinter Publicações Ltda DO - 10.1055/s-0037-1615257 UR - http://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0037-1615257 ER -