A novel dysfunctional protein C (protein C Padua 2) associated with a thrombotic tendency: substitution of Cys for Arg-1 results in a strongly reduced affinity for binding of Ca++ - Girolami, A; Simioni, P; Girolami, B; Marchiori, A; Millar, DS; Bignell, P; Kakkar, VV; Cooper, DN (Br J Haematol, 1993)