A patient with von Willebrand’s disease characterized by a compound heterozygosity for a substitution of Arg854 by Gln in the putative factor-VIII-binding domain of von Willebrand factor (VWF) on one allele and very low levels of mRNA from the second VWF allele - Peerlinck, K; Eikenboom, JC; Ploos Van Amstel, HK (Br J Haematol, 1992)
et al.