The PREMIER study: A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment. - Breedveld, FC; Weisman, MH; Kavanaugh, AF (Arthritis Rheum, 2006)
et al.