TY - JOUR AU - Khurshid, Zohaib; Mali, Maria; Adanir, Necdet; Zafar, Muhammad Sohail; Khan, Rabia Sannam; Latif, Muhammad TI - Periostin: Immunomodulatory Effects on Oral Diseases SN - 1305-7456 SN - 1305-7464 PY - 2020 JO - Eur J Dent JF - European Journal of Dentistry LA - EN VL - 14 IS - 03 SP - 462 EP - 466 DA - 2020/07/20 KW - biomarkers KW - oral KW - health KW - periostin and periodontitis AB - Periostin is a microcellular adapter protein. It plays a wide range of essential roles during the development and in immunomodulation. Periostin is a prominent contributor during the process of angiogenesis, tumorigenesis, and cardiac repair. It is expressed in periodontal ligaments, tendons, skin, adipose tissues, muscle, and bone. This is a protein-based biomolecule that has the diagnostic and monitoring capability and can potentially be used as a biomarker to detect physiological and pathological conditions. The aim of the present review was to explore the periostin morphology and associated structural features. Additionally, periostin’s immunomodulatory effects and associated biomarkers in context of oral diseases have been discussed. PB - Thieme Medical and Scientific Publishers Private Ltd. DO - 10.1055/s-0040-1714037 UR - http://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0040-1714037 ER -