TY - JOUR AU - Allen, Ashley; Hoang, Christine; Sangha, Roopina TI - COVID-19-Associated Coagulopathy in the Peripartum Setting: A Case Report SN - 2157-6998 SN - 2157-7005 PY - 2022 JO - AJP Rep JF - American Journal of Perinatology Reports LA - EN VL - 12 IS - 01 SP - e33 EP - e35 DA - 2022/02/04 KW - COVID-19 KW - coagulopathy KW - D-dimer KW - peripartum KW - anticoagulation AB - Sepsis-induced coagulopathy (SIC) scoring and D-dimer can be used to recognize COVID-19-induced coagulopathy, but the utility of these is largely unknown in the peripartum setting and leaves anticoagulation guidance unclear. We present the case of a critically ill postpartum patient with COVID-19 infection. This patient presented with clinical signs of COVID-19 infection and developed acute respiratory failure requiring invasive mechanical ventilation and subsequent cesarean delivery at 34 weeks. She initially improved postoperatively but deteriorated after postoperative day 5. She was found to have a very elevated D-dimer of 58 μg/mL and anticoagulation was escalated to full dosing. She required prolonged mechanical ventilation and deceased after developing gram-positive cocci bacteremia. This case demonstrates that recognition and management of COVID-19-associated coagulopathy can be confusing in the peripartum period and studies are needed to validate D-dimer and SIC scoring in this population of patients. PB - Thieme Medical Publishers, Inc. DO - 10.1055/s-0041-1742237 UR - http://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0041-1742237 ER -