An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR-gamma). - Lehmann,J.M.; Moore,L.B.; Smitholiver,T.A.; Wilkison,W.O.; Willson,T.M.; Kliewer,S.A. (J Biol Chem, 1995)