Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. - Deeb,S.S.; Fajas,L.; Nemoto,M.; Pihlajamaki,J.; Mykkanen,L.; Kuusisto,J.; Laakso,M.; Fujimoto,W.; Auwerx,J. (Nat Genet, 1998)