Tissue Doppler imaging consistently detects myocardial abnormalities in patients with hypertrophic cardiomyopathy and provides a novel means for an early diagnosis before and independently of hypertrophy. - Nagueh,S.; Bachinski,L.; Meyer,D.; Hill,R.; Zoghbi,W.A.; Tam,J.W.; Quinones,M.A.; Roberts,R.; Marian,A.J. (Circulation, 2001)