Rapid peptide turnover and inefficient presentation of exogenous antigen critically limit the activation of self-reactive CTL by dendritic cells. - Ludewig,B.; McCoy,K.; Pericin,M.; Ochsenbein,A.F.; Dumrese,T.; Odermatt,B.; Toes,R.E.; Melief,C.J.; Hengartner,H.; Zinkernagel,R.M. (J Immunol, 2001)