Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long- term neurological gene therapy for chronic diseases - Thomas,C.E.; Schiedner,G.; Kochanek,S.; Castro,M.G.; Lowenstein,P.R. (Proc Natl Acad Sci USA, 2000)