Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. - Slamon,D.J.; Leyland-Jones,B.; Shak,S.; Fuchs,H.; Paton,V.; Bajamonde,A.; Fleming,T.; Eiermann,W.; Wolter,J.; Pegram,M.; Baselga,J.; Norton,L. (N Engl J Med, 2001)