Administration of nitrit oxide synthase inhibitor NG-methyl-L-arginine hydrochloride (546C88) by intravenous infusion for up to 72 hours can promote the resolution of shock in patients with severe sepsis: Results of a randomized, double-blind, placebo-controlled multicenter study. - Bakker,J.; Grover,R.; McLukie,A.; Holzapfel,L.; Andersson,J.; Lodato,R.; Watson,D.; Grossmann,S.; Donaldson,J.; Takala,J. (Crit Care Med, 2004)