The hypothyroidism in an Inbred kindred with congenital thyroid hormone and glucocorticoid deficiency is due to a mutation producing a truncated thyrotropin receptor. - Tiosano,D.; Pannain,S.; Vassart,G.; Parma,J.; Gershoni-Baruch,R.; Mandel,H.; Lotan,R.; Zaharan,Y.; Pery,M.; Weiss,R.E.; Refetoff,S.; Hochberg,Z.E. (Thyroid, 1999)