Duloxetine is both an inhibitor and a substrate of cytochrome P4502D6 in healthy volunteers - Skinner,M.H.; Kuan,H.Y.; Pan,A.; Sathirakul,K.; Knadler,M.P.; Gonzales,C.R.; Yeo,K.P.; Reddy,S.; Lim,M.; Ayan-Oshodi,M.; Wise,S.D. (Clin Pharmacol Therapeutics, 2003)