The zona reticularis is the site of biosynthesis of dehydroepiandrosterone and dehydroepiandrosterone sulfate in the adult human adrenal cortex resulting from its low expression of 3β-hydroxysteroid dehydrogenase. - Endoh,A.; Kristiansen,SB.; Casson,PR.; Buster,JE.; Hornsby,PJ. (J Clin Endocrinol Metab, 1996)