The natural occurrence of human fibrinogen variants disrupting inter-chain disulfide bonds (AαCys36Gly, AαCys36Arg and AαCys45Tyr) confirms the role of N-terminal Aa disulfide bonds in protein assembly and secretion - Hanss, M; Pouymayou, C; Blouch, M-T (Haematologica, 2011)
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