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Pneumologie 2023; 77(11): 947-955
DOI: 10.1055/a-2145-4832
Übersicht

Neue Aspekte bei der pulmonalen Hypertonie im Kindesalter – kommentierte 2022ERS/ESC-PH-Guidelines

New aspects in pediatric pulmonary hypertension – Commented 2022ERS/ESC-PH guidelines
Christian Apitz
1   Universitätsklinik für Kinder- und Jugendmedizin Ulm, Sektion Pädiatrische Kardiologie, Ulm, Deutschland
,
Rainer Kozlik-Feldmann
2   Klinik und Poliklinik für Kinderkardiologie, Universitäres Herz- und Gefäßzentrum Hamburg, Klinik und Poliklinik für Kinderherzmedizin und Erwachsene mit angeborenen Herzfehlern, Hamburg, Deutschland
,
Christina A. Eichstaedt
3   Zentrum für Pulmonale Hypertonie, Thoraxklinik Heidelberg am Universitätsklinikum Heidelberg, Heidelberg, Deutschland; TLRC am Deutschen Zentrum für Lungenforschung (DZL), Heidelberg, Deutschland; Institut für Humangenetik, Universität Heidelberg, Heidelberg, Deutschland
,
Matthias Gorenflo
4   Klinik für Kinderkardiologie und angeborene Herzfehler, Universitätsklinikum Heidelberg, Heidelberg, Deutschland
,
Astrid E. Lammers
5   Klinik für Pädiatrische Kardiologie und Klinik für Kardiologie III: Angeborene Herzfehler (EMAH) und Klappenerkrankungen, Universitätsklinikum Münster, Münster, Deutschland
,
Ralf Geiger
6   Univ.-Klinik für Pädiatrie III, Kardiologie, Pneumologie, Allergologie, Cystische Fibrose, Innsbruck, Österreich
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Zusammenfassung

Lungenhochdruck im Kindesalter unterscheidet sich von dem des Erwachsenenalters insbesondere durch die spezifische Pathophysiologie der herzfehlerassoziierten pulmonalarteriellen Hypertonie, das Vorkommen von entwicklungsbedingten Lungenerkrankungen und die häufige Assoziation mit chromosomalen, genetischen und syndromalen Auffälligkeiten. Die Behandlung von Kindern mit pulmonaler Hypertonie erfordert einen auf das Kindesalter zugeschnittenen modifizierten diagnostischen Algorithmus sowie pathophysiologisch orientierte therapeutische Strategien. In den aktuellen 2022 ERS/ESC-Pulmonale Hypertonie-Leitlinien werden die spezifischen Besonderheiten des Lungenhochdrucks im Kindesalter in einem Extrakapitel hervorgehoben und in diesem Artikel vom Kreis der Autorenschaft kommentiert.

Abstract

Pulmonary hypertension (PH) in childhood differs from that of adulthood particularly in the specific pathophysiology of congenital heart disease-associated pulmonary arterial hypertension, the presence of developmental lung disease, and the frequent association with chromosomal, genetic, and syndromal abnormalities. Treatment of children with PH requires a modified diagnostic algorithm tailored to childhood, as well as pathophysiologically oriented therapeutic strategies. In the current 2022 ERS/ESC-PH guidelines, the specific features of PH in children are highlighted in its own chapter and commented on by the authorship group in this article.

Schlüsselwörter

pädiatrische pulmonale Hypertonie - pulmonalarterielle Hypertonie - angeborene Herzfehler - pädiatrische Kardiologie

Keywords

pediatric pulmonary hypertension - pulmonary arterial hypertension - congenital heart disease - pediatric cardiology


Publication History

Article published online:
14 November 2023

© 2023. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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