ACUTE COLONIC OBSTRUCTION IN PATIENTS TREATED WITH PALLIATIVE INTENTION. FACTORS RELATED TO MORTALITY

Aims To evaluate factors involved in mortality in patients who presented an acute colonic obstruction treated without curative intention. Our objective was to determine the influence of endoscopic stent.

Methods We performed an observational and retrospective study of patients attended in a single center for acute colonic obstruction caused by cancer between 2007 and 2014. There were only included patients with palliative intention, with metastasis at the time of diagnosis, those treated with surgery with R1-R2 resection or treated with a colonic stent. We calculated the hazard ratio of the event death.

Results There were included data from 165 patients with a median of follow up of 8,1 months. In [table 1] we describe some of the basal characteristics of the patients.

Tab. 1

	n (%)
M1	132 (81)
Stent	113 (68)
Surgery	97 (55)
Chemotherapy	81 (48)

At the end of the study 13 patients (7,9%) were alive. In the univariate analysis age HR 1,03 (p=0,00), Charlson score HR 0,03 (p=1,09), surgery HR 0,33 (p=0,00), residual tumour HR 3,41 (p=0,00) and chemotherapy HR 0,23 (p=0,00) were associated to mortality. In the multivariate analysis allocation of a stent, surgery, absence of metastatic disease, complete resection of tumoral tissue and chemotherapy were associated with lower mortality.

Conclusions In our study, colonic stent placement was associated with better survival in palliative acute colonic obstruction.