Endoscopy 2002; 34(3): 195-198
DOI: 10.1055/s-2002-20290
Original Article

© Georg Thieme Verlag Stuttgart · New York

Effect of Esophageal Variceal Band Ligation on Hemorrhoids, Anorectal Varices, and Portal Hypertensive Colopathy

S.  P.  Misra 1 , V.  Misra 2 , M.  Dwivedi 1
  • 1Dept. of Gastroenterology, MLN Medical College, Allahabad, India
  • 2Dept. of Pathology, MLN Medical College, Allahabad, India
Further Information

Publication History

21 June 2001

29 August 2001

Publication Date:
22 February 2002 (online)

Background and Study Aims: Although it is known that obliteration of esophageal varices following endoscopic variceal band ligation results in an increase in the incidence of portal hypertensive gastropathy, the effect of variceal ligation on hemorrhoids, anorectal/colonic varices and portal hypertensive colopathy is not known. The aim of this study was to investigate the effect of endoscopic variceal band ligation on hemorrhoids, anorectal/colonic varices and portal hypertensive colopathy.
Patients and Methods: A total of 60 consecutive patients with cirrhosis of the liver and portal hypertension were prospectively studied. Upper gastrointestinal endoscopy and full-length colonoscopy were carried out before the patients underwent endoscopic variceal band ligation for esophageal varices and after obliteration of the varices following band ligation.
Results: Obliteration of esophageal varices by endoscopic variceal band ligation did not affect the incidence of hemorrhoids (37 % before and after), anorectal varices (40 % before and after), and portal hypertensive colopathy (57 % before and after).
Conclusions: It is concluded that esophageal variceal band ligation does not affect the incidence of hemorrhoids, anorectal varices or portal hypertensive colopathy in patients with cirrhosis of the liver.

References

  • 1 McCormack T T, Sims J, Eyre-Brook I. et al . Gastric lesions in portal hypertension: inflammatory gastritis or congestive gastropathy?.  Gut. 1985;  26 1226-1232
  • 2 Papazian A, Braillon A, Dupas J L. et al . Portal hypertensive gastric mucosa: an endoscopic study.  Gut. 1986;  27 1199-1203
  • 3 Tabibian N, Graham D Y. Source of upper gastrointestinal bleeding in patients with esophageal varices seen at endoscopy.  J Clin Gastroenterol. 1987;  9 279-282
  • 4 Baxter J, Dobbs B. Portal hypertensive gastropathy.  J Gastroenterol Hepatol. 1988;  3 635-644
  • 5 Triger D, Hosking S. The gastric mucosa in portal hypertension.  J Hepatol. 1989;  8 267-272
  • 6 Misra S P, Dwivedi M, Misra V. et al . Endoscopic and histological appearance of the gastric mucosa in patients with portal hypertension.  Gastrointest Endosc. 1990;  36 575-579
  • 7 Viggiano T R, Gostout C J. Portal hypertensive intestinal vasculopathy: a review of the clinical, endoscopic and histopathological features.  Am J Gastroenterol. 1992;  87 944-954
  • 8 Iwao T, Toyonaga A, Sumino M. et al . Portal hypertensive gastropathy in patients with cirrhosis.  Gastroenterology. 1992;  102 2060-2065
  • 9 Kozarek R A, Botoman V A, Bredfeldt J E. et al . Portal colopathy: prospective study in patients with portal hypertension.  Gastroenterology. 1991;  101 1192-1197
  • 10 Naveau S, Bedossa P, Poynard T. et al . Portal hypertensive colopathy. A new entity.  Dig Dis Sci. 1991;  36 1774-1781
  • 11 Scandalis N, Archimandritis A, Kastanas K. et al . Colon findings in cirrhotics with portal hypertension. A prospective colonoscopic and histological study.  J Clin Gastroenterol. 1994;  18 325-328
  • 12 Chen L S, Lin H C, Lee F Y. et al . Portal hypertensive colopathy in patients with cirrhosis.  Scand J Gastroenterol. 1996;  31 490-494
  • 13 Ganguly S, Sarin S K, Bahtia V, Lahoti D. The prevalence and spectrum of colonic lesions in patients with cirrhotic and noncirrhotic portal hypertension.  Hepatology. 1995;  21 1226-1231
  • 14 Misra S P, Dwivedi M, Misra V. Prevalence and factors influencing hemorrhoids, anorectal varices and colopathy in patients with portal hypertension.  Endoscopy. 1996;  29 340-345
  • 15 Eleftheriadis E, Kotazampassi K, Karakavelas G. et al . Portal hypertensive colopathy: endoscopic, hemodynamic and morphometric study.  Dig Endosc. 1993;  5 224-230
  • 16 Rabinovitz M, Schade P R, Didzans V J. et al . Colonic disease in cirrhosis: a endoscopic evaluation in 412 patients.  Gastroenterology. 1990;  99 195-199
  • 17 Misra S P, Dwivedi M, Misra V. Effect of esophageal variceal sclerotherapy on hemorrhoids, anorectal varices and portal colopathy.  Endoscopy. 1999;  31 741-744
  • 18 Sarin S K, Govil A, Jain A K. et al . Prospective randomized trial of endoscopic sclerotherapy versus variceal band ligation for esophageal varices: influence on gastropathy, gastric varices and variceal recurrence.  J Hepatol. 1997;  26 826-832
  • 19 de la Pena , Rivero M, Sanches E. et al . Variceal ligation compared to sclerotherapy for variceal hemorrhage: prospective randomized trial.  Gastrointest Endosc. 1999;  49 417-423
  • 20 Sauerbruch T, Schepkem M. Sclerotherapy is out - nearly.  Endoscopy. 1997;  29 281-282
  • 21 Conn H O. Ammonia tolerance in the diagnosis of esophageal varices. A comparison of endoscopic, radiologic, and biochemical techniques.  J Lab Clin Med. 1967;  70 442-449
  • 22 Pugh R NH, Murray-Lyon J M, Dawson J L. et al . Transection of the oesophagus for bleeding oesophageal varices.  Br J Surg. 1973;  60 646-649
  • 23 Corbishley C M, Saverymuttu S, Maxwell J D. Use of endoscopic biopsy for diagnosing congestive gastropathy.  J Clin Pathol. 1988;  41 1187-1190
  • 24 Foster P N, Wyatt J I, Bullimore D W, Losowsky M S. Gastric mucosa in patients with portal hypertension: prevalence of capillary dilatation and Campylobacter pylori.  J Clin Pathol. 1989;  42 919-921
  • 25 Tarnawski A, Sarfeh I J, Stachura J. et al . Microvascular abnormalities of the portal hypertensive gastric mucosa.  Hepatology. 1988;  8 1488-1494
  • 26 Quintero E, Pique J M, Bombi J A. et al . Gastric mucosal vascular ectasias causing bleeding in cirrhosis.  Gastroenterology. 1987;  93 1054-1061
  • 27 Saperas E, Pigue J M, Perez-Ayuso R P. et al . Comparison of snare and large forceps biopsy in the histologic diagnosis of gastric vascular ectasia in cirrhosis.  Endoscopy. 1989;  21 165-167
  • 28 Misra V, Misra S P, Dwivedi M. Thickened gastric mucosal capillary wall: a histological marker for portal hypertension.  Pathology. 1998;  30 10-13
  • 29 Waxman J S, Tarkin N, Dave P, Waxman M. Fatal hemorrhage from rectal varices: report of two cases.  Dis Colon Rectum. 1984;  27 749-750
  • 30 Foutch P G, Sivak M V Jr. Colonic variceal hemorrhage after endoscopic injection sclerosis of esophageal varices: a report of three cases.  Am J Gastroenterol. 1984;  79 756-760
  • 31 Herman B E, Baum S, Denobile J, Volpe R J. Massive bleeding from rectal varices.  Am J Gastroenterol. 1993;  88 939-942
  • 32 Lebrec D, DeFleury P, Rueff B. et al . Portal hypertension, size of esophageal varices, and risk of gastrointestinal bleeding in cirrhosis.  Gastroenterology. 1980;  79 1139-1144
  • 33 lwao T, Toyonaga A, Oho K. et al . Portal hypertensive gastropathy develops less in patients with cirrhosis and fundal varices.  J Hepatol. 1997;  26 1235-1241
  • 34 Thompson W HF. The nature of haemorrhoids.  Br J Surg. 1975;  62 542-552
  • 35 Bernstein W C. What are hemorrhoids and what is their relationship to the portal system?.  Dis Colon Rectum. 1983;  26 829-834

S. P. Misra, M.D., D.M.

Dept. of Gastroenterology · MLN Medical College

Allahabad 211001 · India

Fax: + 91-532-611420

Email: spmisra@rediffmail.com

    >