Die schwefelhaltigen Aminosäuren

Zusammenfassung

Der Organismus benötigt für den Energiefluss, die Signalübertragung und die Heilungs- und Entgiftungsprozesse redoxaktiven Schwefel, der durch die Aminosäure Cystein bereitgestellt wird. Cystin und Methionin aus der Nahrung liefern diesen Baustein. Pflanzliche Proteine enthalten im Vergleich zu tierischen relativ zueinander mehr Cystein als Methionin. Ein Vergleich der Häufigkeit von Herz-Kreislauf-Erkrankungen zu den Essgewohnheiten lässt eine Parallelität der Zusammenhänge erkennen zu den biochemischen Abläufen des Schwefelstoffwechsels bei systemischen Erkrankungen. Danach ist einer Ernährung mit vorwiegend pflanzlichem Protein aufgrund des überwiegenden Cystingehalts der Vorzug zu geben.

Summary

The organism requires redox-active sulphur for energy flow, signal transduction as well as for healing and detoxification. It is provided by the amino acid cysteine. Cystine and ―methionine from food protein are the source of cysteine. The transformation of methionine to cysteine via transmethylation and transsulfuration reactions is causing additional cascades of metabolic signals. Nutritional proteins derived from animal or plant show distinct differences in the ratio of methionine versus cystine content. Striking parallels occur when comparing epidemiology of cardiovascular and cancer disease in correlation to ―dietary habits and the relationship of sulphur amino acid metabolism to the ratio of ―methionine versus cystein content in food. Accordingly, diets containing mainly plant ―derived proteins should be preferred due to the predominant cystine content. Characteristics of the inflammation syndrome as result of oxidative stress (e. g. loss of glutathione. ―hyperhomocysteinemia, and apoptosis) can be reduced, prevented, or treated by taking diets rich in cystine/cysteine or supplement therapy with acetyl-cysteine. Further investigations on the influence of sulphur amino acids in food on general health may be a promis―ing target for future research.

Schlüsselwörter

Cystein - Methionin - Homocystein - Schwefelstoffwechsel - Entzündung - Nahrungsprotein

Keywords

Cysteine - methionine - homocysteine - sulfur metabolism - inflammation - food protein

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