Thromb Haemost 2002; 88(02): 368
DOI: 10.1055/s-0037-1613217
Letters to the Editor
Schattauer GmbH

Relationship between C-5T Kozak, C807T Genotypes and Expression of Glycoproteins Ibα and Ia-IIa at Platelet Surface: From Genotype to Phenotype

L Macchi
1   Laboratoire d’hématologie et des maladies du sang
,
N Sorel
1   Laboratoire d’hématologie et des maladies du sang
,
S Brabant
1   Laboratoire d’hématologie et des maladies du sang
,
L Christiaens
2   Département de cardiologie
,
G Mauco
3   EA 1223, GEMCI, Faculté de Médecine et Pharmacie, Hôpital La Milétrie, CHU Poitiers, Poitiers, France
› Author Affiliations
Further Information

Publication History

Received 10 March 2002

Accepted after revision 22 April 2002

Publication Date:
07 December 2017 (online)

 

 
  • References

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  • 2 Kunicki TJ, Kritzik M, Annis DS, Nugent DJ. Hereditary variation in platelet integrin α2β1 density is associated with two silent polymorphisms in the α2 gene coding sequence. Blood 1997; 89: 1939-43.
  • 3 Afshar-Karghan V, Li CQ, Khoshnevis-Asl M, Lopez JA. Kozak sequence polymorphism of the glycoprotein (GP) Ibα gene is a major determinant of the plasma membrane levels of the platelet GP Ib-IX-V complex. Blood 1999; 94: 186-91.
  • 4 Corral J, Lozano ML, Gonzalez-Conejero R, Martinez C, Iniesta JA, Rivera J, Vicente V. A common polymorphism flanking the ATG initiator codon of GpIba does not affect expression and is not a major risk factor for arterial thrombosis. Thromb Haemost 2000; 83: 23-8.
  • 5 Croft SA, Hampton KK, Sorrel JA, Steeds RP, Channer KS, Samani NJ, Daly ME. The GPIa C807T dimorphism associated with platelet collagen receptor density is not a risk factor for myocardial infarction. Br J Haematol 1999; 106: 771-6.