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Thromb Haemost 2003; 90(02): 165-166
DOI: 10.1055/s-0037-1613488
Editorial Focus
Schattauer GmbH

Optimizing initial therapy of acute venous thromboembolism

Andrew I. Schafer
1   Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, USA
› Institutsangaben
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Publikationsverlauf

Received 30. Mai 2003

Accepted 02. Juni 2003

Publikationsdatum:
09. Dezember 2017 (online)

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  • References

  • 1 Barritt DW, Jordan SC. Anticoagulant drugs in the treatment of pulmonary embolism: a controlled trial. Lancet 1960; 1: 1309-12.
    CrossrefPubMedGoogle Scholar
  • 2 Hirsh J, Warkentin TE, Shaughnessy SG. et al. Heparin and low-molecular-weight heparin. Mechanisms of action, pharmacokinetics, dosing, monitoring, efficacy, and safety. Chest 2001; 119: S64-S94.
    CrossrefPubMedGoogle Scholar
  • 3 Breddin HK, Hach-Wunderle V, Nakov R, Kakkar VV. for the CORTES Investigators. Effects of a low-molecular-weight heparin on thrombus regression and recurrent thromboembolism in patients with deep-vein thrombosis. N Engl J Med 2001; 344: 626-31.
    CrossrefPubMedGoogle Scholar
  • 4 Kakkar VV, Hoppenstead DA, Fareed J. et al. Randomized trial of different regiments of heparin and in vivo thrombin generation in acute deep vein thrombosis. Blood 2002; 99: 1965-70.
    CrossrefPubMedGoogle Scholar
  • 5 Harenberg J, Huisman MV, Tolle AR, Breddin HK, Kirchmaier CM. Reduction in thrombus extension and clinical end points in patients after initial treatment for deep vein thrombosis with the fixed-dose body weight-independent low molecular weight heparin certoparin. Semin Thromb Hemost 2001; 27: 513-8.
    Artikel in Thieme ConnectPubMedGoogle Scholar
  • 6 Ellison MJ, Sawyer WT, Mills TC. Calculation of heparin dosage in a morbidly obese woman. Clin Pharm 1989; 8: 65-8.
    PubMedGoogle Scholar
  • 7 Cheymol G. Drug pharmacokinetics in the obese. Fundam Clin Pharmacol 1988; 2: 239-56.
    CrossrefPubMedGoogle Scholar
  • 8 Riess H, Koppenhager K, Tolle A. et al. for the TH-4 Study Group. Fixed-dose, body weight-independent subcutaneous low molecular weight heparin Certoparin compared with adjusted-dose intravenous unfractionated heparin in patients with proximal deep vein thrombosis. Thromb Haemost 2003; 90: 252-9.
    Artikel in Thieme ConnectPubMedGoogle Scholar
  • 9 Anand SS, Bates S, Ginsberg JS. et al. Recurrent venous thrombosis and heparin therapy. An evaluation of the importance of early activated partial thromboplastin times. Arch Intern Med 1999; 159: 2029-32.
    CrossrefPubMedGoogle Scholar
  • 10 The Rembrandt Investigators. Treatment of proximal deep vein thrombosis with a novel synthetic compound (SR90107A/ORG31540) with pure anti-factor Xa activity: a phase II evaluation. Circulation 2000; 102: 2726-31.
    CrossrefPubMedGoogle Scholar