Endoscopy 2020; 52(S 01): S81
DOI: 10.1055/s-0040-1704244
ESGE Days 2020 oral presentations
Friday, April 24, 2020 08:30 – 10:30 EUS-guided interventions Liffey Meeting Room 3
© Georg Thieme Verlag KG Stuttgart · New York

PATENCY OF EUS-GUIDED GASTROENTEROSTOMY IN THE TREATMENT OF MALIGNANT GASTRIC OUTLET OBSTRUCTION

JB Kastelijn
1   University Medical Center Utrecht, Department of Gastroenterology and Hepatology, Utrecht, Netherlands
,
LMG Moons
1   University Medical Center Utrecht, Department of Gastroenterology and Hepatology, Utrecht, Netherlands
,
FJ Garcia-Alonso
2   Hospital Universitario Rio Hortega, Department of Gastroenterology and Hepatology, Valladolid, Spain
,
M Pérez-Miranda
2   Hospital Universitario Rio Hortega, Department of Gastroenterology and Hepatology, Valladolid, Spain
,
V Masaryk
3   SRH Wald-Klinikum, Department of Gastroenterology and General Internal Medicine, Gera, Germany
,
U Will
3   SRH Wald-Klinikum, Department of Gastroenterology and General Internal Medicine, Gera, Germany
,
I Tarantino
4   Mediterranean Institute for Transplantation and Advanced Specialized Therapies (IsMeTT), Gastroenterology and Endoscopy Unit, Palermo, Italy
,
HM van Dullemen
5   University Medical Center Groningen, Department of Gastroenterology and Hepatology, Groningen, Netherlands
,
R Bijlsma
6   Martini Hospital, Department of Gastroenterology and Hepatology, Groningen, Netherlands
,
JW Poley
7   Erasmus MC University Medical Center, Department of Gastroenterology and Hepatology, Rotterdam, Netherlands
,
MP Schwartz
8   Meander Medical Center, Department of Gastroenterology and Hepatology, Amersfoort, Netherlands
,
FP Vleggaar
1   University Medical Center Utrecht, Department of Gastroenterology and Hepatology, Utrecht, Netherlands
› Author Affiliations
Further Information

Publication History

Publication Date:
23 April 2020 (online)

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    Aims Endoscopic ultrasonography-guided gastroenterostomy (EUS-GE) using a Lumen Apposing Metal Stent (LAMS), is a novel, minimally invasive technique in the palliative treatment of malignant gastric outlet obstruction (GOO). Several studies have demonstrated feasibility and safety of EUS-GE. However, evidence on long-term durability is limited. The aim of this study is to evaluate long-term patency of EUS-GE with a LAMS in the treatment of malignant GOO.

    Methods A multicenter international retrospective study was performed in seven centers from four European countries. Patients who underwent EUS-GE with a LAMS (Hot AXIOS stent) between March 2015 and March 2019 for palliative treatment of symptomatic malignant GOO were included. Primary endpoint was recurrent obstruction, secondary endpoints were technical success, clinical success, adverse events and survival.

    Results A total of 45 patients (48.9% male; mean age 69.9 ± 12.3 years) were included in this study. Median follow-up was 59 days (IQR 41-128). Recurrent obstruction after initial clinical success occurred in two patients (6.1%), after 33 and 283 days of follow-up. Technical success was achieved in 38 (84.4%) patients. Clinical success was achieved in 33 (73.3%) cases. Adverse events occurred in 12 (26.7%) patients, five (11.1%) of which were fatal.

    Conclusions A total of 45 patients (48.9% male; mean age 69.9 ± 12.3 years) were included in this study. Median follow-up was 59 days (IQR 41-128). Recurrent obstruction after initial clinical success occurred in two patients (6.1%), after 33 and 283 days of follow-up. Technical success was achieved in 38 (84.4%) patients. Clinical success was achieved in 33 (73.3%) cases. Adverse events occurred in 12 (26.7%) patients, of which five (11.1%) were fatal.


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