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DOI: 10.1055/s-0040-1704493
UPPER GASTROINTESTINAL BLEEDING SECONDARY TO BURKITT LYMPHOMA, AN UNCOMMON BUT VERY AGGRESSIVE CAUSE OF GASTRIC CANCER
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Publication Date:
23 April 2020 (online)
Lymphoma is the second most common type of gastric cancer, especially MALT and diffuse large B cells lymphomas. A very rare but highly aggressive lymphoma is Burkitt lymphoma. Man, 72 years with epigastralgia, melena and anemia. In urgent gastroscopy, a large excavated ulcer is observed on the underside of the antrum (1-3). Biopsies show CD20+/bcl-6+/CD10+ lymphoid cells on the lamina propria, over-expression of c-myc and Ki67>90%, compatible with Burkitt lymphoma. PET/CT (4) shows large gastric hypermetabolic mass, with multiple intra-abdominal nodules. Chemotherapy (R-DA-EPOCH scheme) achieves complete metabolic remission in PET/CT at the end of treatment (5).
