Endoscopy 2020; 52(S 01): S285
DOI: 10.1055/s-0040-1704900
ESGE Days 2020 ePoster presentations
Colon and rectum 09:00–17:00 Thursday, April 23, 2020 ePoster area
© Georg Thieme Verlag KG Stuttgart · New York

THE ADDITION OF CASTOR OIL AS A BOOSTER IN COLON CAPSULE REGIMENS SIGNIFICANTLY IMPROVES COMPLETION RATES AND POLYP DETECTION

S Semenov
1   Trinity Academic Gastroenterology Group, Tallaght University Hospital, Dublin, Ireland
2   Tallaght University Hospital, Department of Gastroenterology, Dublin, Ireland
,
R Atiyekeogbebe
1   Trinity Academic Gastroenterology Group, Tallaght University Hospital, Dublin, Ireland
,
MS Ismail
1   Trinity Academic Gastroenterology Group, Tallaght University Hospital, Dublin, Ireland
2   Tallaght University Hospital, Department of Gastroenterology, Dublin, Ireland
,
S Sihag
1   Trinity Academic Gastroenterology Group, Tallaght University Hospital, Dublin, Ireland
2   Tallaght University Hospital, Department of Gastroenterology, Dublin, Ireland
,
E McCarthy
1   Trinity Academic Gastroenterology Group, Tallaght University Hospital, Dublin, Ireland
2   Tallaght University Hospital, Department of Gastroenterology, Dublin, Ireland
,
B Ryan
2   Tallaght University Hospital, Department of Gastroenterology, Dublin, Ireland
,
N Breslin
2   Tallaght University Hospital, Department of Gastroenterology, Dublin, Ireland
,
A O’Connor
1   Trinity Academic Gastroenterology Group, Tallaght University Hospital, Dublin, Ireland
2   Tallaght University Hospital, Department of Gastroenterology, Dublin, Ireland
,
D McNamara
1   Trinity Academic Gastroenterology Group, Tallaght University Hospital, Dublin, Ireland
2   Tallaght University Hospital, Department of Gastroenterology, Dublin, Ireland
› Author Affiliations
Further Information

Publication History

Publication Date:
23 April 2020 (online)

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    Aims Incomplete excretion rates are problematic for colon capsule endoscopy (CCE). Widely available booster regimens perform poorly. Recently published same day CCE protocol in IBD using castor oil appeared effective. Our aim was to assess the effectiveness of adding castor oil as an additional booster in our CCE practice.

    Methods All patients received split bowel preparation with Moviprep© prior to CCE procedures. Control booster regimen included 750 ml of Moviprep© with 750 ml of water on reaching the small bowel, a further 250 ml of Moviprep© with 250 ml of water 3 hours later and a bisacodyl suppository 10 mg after 8 hours, if not excreted. Cases followed the same regimen with the addition of 15 ml of castor oil given with booster 1. A nested case control design with 4:1 (control: case) ratio was employed. Basic demographics, completion rates, image quality, transit time and polyp detection were compared between groups, using t or chi2 tests as appropriate.

    Results 140 CCEs (mean age 60 years (19–89), 52% females, n = 73), including 28 cases have been analysed. Cases and controls were matched for age and gender. Overall CCE completion was 75% (105/140), image quality was adequate in 83% (116/140), mean transit time 3.5 hours (0.5–12.5) and a polyp detection rate of 52% (73/140).

    Completion rates were significantly higher with castor oil, cases 89% (25/28) vs 71% (80/112), p = 0.03. Similarly, polyp detection rates were higher 79% (22/28) vs 46% (51/112), p = 0.001, with an OR of 4.4, 95%CI 1.65–11.64. Transit times were similar, 3 and 3.6 hours, respectively. However, image quality was significantly poorer in cases being reported as adequate in 71% (20/28) vs 86% (96/112), p = 0.03.

    Conclusions In our cohort, castor oil addition as a CCE booster significantly improved completion rates and polyp detection. Timing of castor oil administration may need to be adjusted to optimise proximal image quality.


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