Endoscopy 2021; 53(S 01): S92-S93
DOI: 10.1055/s-0041-1724489
Abstracts | ESGE Days
ESGE Days 2021 Oral presentations
Saturday, 27 March 2021 16:00 – 16:45 All about Zenker’s Room 6

Peroral Endoscopic Myotomy In The Management Of Zenker’s Diverticulum: A Retrospective Multicenter Study

A Budnicka-Borkowicz
1   Department of Gastroenterological Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
2   Department of Gastroenterology, Hepatology and Oncology, Medical Center for Postgraduate Education, Warsaw, Poland
,
W Januszewicz
1   Department of Gastroenterological Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
2   Department of Gastroenterology, Hepatology and Oncology, Medical Center for Postgraduate Education, Warsaw, Poland
,
A Białek
3   Department of Gastroenterological Oncology, Szczecin, Poland
,
M Spychalski
4   Department of Gastroenterological Oncology, Brzeziny, Poland
,
J Reguła
1   Department of Gastroenterological Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
2   Department of Gastroenterology, Hepatology and Oncology, Medical Center for Postgraduate Education, Warsaw, Poland
,
M Kamiński
1   Department of Gastroenterological Oncology, Maria Sklodowska-Curie National Research Institute of Oncology, Warsaw, Poland
2   Department of Gastroenterology, Hepatology and Oncology, Medical Center for Postgraduate Education, Warsaw, Poland
5   University of Oslo, Institute of Health and Society, Oslo, Norway
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    Aims Peroral endoscopic myotomy (POEM) is an emerging technique in the treatment of Zenker’s diverticulum (ZD). This study aimed to analyze the feasibility of Zenker’s POEM (Z-POEM) in a multicenter setting and assess its performance using a validated Kothari-Haber Scoring System newly developed for symptom measurement in ZD.

    Methods This was a multicenter retrospective study involving 3 Polish tertiary referral endoscopic units. The data of consecutive patients with symptomatic ZD treated with Z-POEM in Poland between May 2019 and August 2020 were retrieved and analyzed. Primary outcome measures were technical success and clinical success rate (<3 points in Kothari-Haber Score at 2-3 months follow-up). Secondary outcome measures included procedures’ duration, length of hospital stay, and adverse events.

    Results 22 patients with symptomatic ZD were included. The mean age was 67.6 (±10.7) years, and 14 (63.6 %) were male. All but 2 patients were treatment naïve. The average size of the ZD was 30 mm (IQR, 24-40 mm). Technical success was achieved in all patients (100 %), whereas clinical success was 90.9 %. The average Kothari-Haber Score was 6.35 before treatment and has dropped to 0.65 after the treatment (P<.0001). The mean procedure time was 48.8 (±19.3) minutes, and the median length of hospital stay was 2 days (IQR, 2-3). Three patients (13.6 %) had post-procedural emphysema, of which two were mild and self-resolving (9.1 %), and one was moderate (4.5 %) and complicated with laryngeal edema and prolonged intubation.

    Conclusions This feasibility study suggests that Z-POEM is a highly effective and safe treatment for ZD, particularly among treatment naïve patients. Comparative studies with other treatment modalities over longer follow-up are warranted.

    Citation: Budnicka-Borkowicz A, Januszewicz W, Białek A et al. OP225 PERORAL ENDOSCOPIC MYOTOMY IN THE MANAGEMENT OF ZENKER’S DIVERTICULUM: A RETROSPECTIVE MULTICENTER STUDY. Endoscopy 2021; 53: S92.


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    Publication History

    Article published online:
    19 March 2021

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