Detection of Colonic Polyps In India – a Large Retrospective Cohort Study (DOCPI-R)

Aims Colorectal cancer (CRC) is an emerging public health problem in Asia and India. However, there is scarcity of data on CRC and adenoma. We aimed to study prevalence and characteristics of colonic polyps in large retrospective cohort.

Methods For this retrospective single center study, all patients with age >18 years undergoing colonoscopy from January 2018 to December 2019 were included. Age, gender and polyp characteristics were collected from endoscopy and histology database. Patients with incomplete histology reports and anal canal polyps were excluded. Based on histology, polyps were divided into adenocarcinoma, adenoma with advanced pathology (AAP; size >10mm, villous morphology or high grade dysplasia), other adenomas and non-adenomas.

Results Overall colon polyp prevalence was 10.18 % (3551/34893). The mean age (SD) was 51.51 (14.84) with 75.4 % males. Of which, 128 (3.6 %) were adenocarcinoma. 1514 (42.64 %) were adenomas; 344 (9.7 %) were AAP and 1170 (32.9 %) were other adenomas. Remaining 1909 (53.8 %) were non-adenomas. Colonic adenoma prevalence after excluding adenocarcinoma was 4.35 % (1514/34893). Adenocarcinoma (68.8 % vs 31.2 %), AAP (70.6 % vs 29.4 %), other adenomas (75.4 % vs 24.6 %) and non-adenomas (76.7 % vs 23.3 %) were significantly higher in male compared to female (p <0.05). Adenomas and adenocarcinoma were more common in left colon and rectum than right colon (p <0.05). The mean age (SD) were significantly lower in non-adenomas than adenocarcinoma, AAP and other adenomas (p 0.0001; 49.25(14.84) vs 55.97 (12.47), 54.78 (16.40), 53.76 (13.71)).

Conclusions The prevalence of colonic adenoma in India is 4.35 %. Male gender and increased age associated with increased risk of colonic adenoma and adenocarcinoma which is more common in left colon and rectum. Prospective multicenter studies are required for evaluation of other risk factors of CRC and colonic adenomas.

Citation: Jagtap N, Inavolu P, Singh A et al. eP207 DETECTION OF COLONIC POLYPS IN INDIA – A LARGE RETROSPECTIVE COHORT STUDY (DOCPI-R). Endoscopy 2021; 53: S166.

Publication History

Article published online:
19 March 2021