Endoscopy 2021; 53(S 01): S214
DOI: 10.1055/s-0041-1724852
Abstracts | ESGE Days
ESGE Days 2021 Digital poster exhibition

Technical Outcomes of Ercp Procedures in Patients With Covid-19

T Voiosu
1   Carol Davila Faculty of Medicine, Internal Medicine/Gastroenterology, Bucharest, Romania
,
A Voiosu
2   Colentina Clinical Hospital, Gastroenterology, Bucharest, Romania
,
I Boškoski
3   Fondazione Policlinico Universitario Agostino Gemelli, Digestive Endoscopy Unit, Rome, Italy
4   Centre for Endoscopic Research Therapeutics and Training (CERTT), Catholic University of Rome, Rome, Italy
,
M Arvanitakis
5   Department of Gastroenterology, Hepatopancreatology, and Digestive Oncology, CUB Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium
,
M Bronswijk
6   Department of Gastroenterology and Hepatology, University Hospitals Gasthuisberg, University of Leuven, Leuven, Belgium
,
M Hollenbach
7   Division of Gastroenterology; Medical Department II (Oncology, Gastroenterology, Hepatology, Pulmonology, Infectious Diseases), University of Leipzig, Leipzig, Germany
,
A Benguș
8   Gastroenterology Department, Colentina Clinical Hospital, Bucharest, Romania
,
P Bălănescu
1   Carol Davila Faculty of Medicine, Internal Medicine/Gastroenterology, Bucharest, Romania
,
B Orlandini
4   Centre for Endoscopic Research Therapeutics and Training (CERTT), Catholic University of Rome, Rome, Italy
,
D Blero
5   Department of Gastroenterology, Hepatopancreatology, and Digestive Oncology, CUB Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium
,
S van der Merwe
6   Department of Gastroenterology and Hepatology, University Hospitals Gasthuisberg, University of Leuven, Leuven, Belgium
,
RB Mateescu
1   Carol Davila Faculty of Medicine, Internal Medicine/Gastroenterology, Bucharest, Romania
,
J Devière
5   Department of Gastroenterology, Hepatopancreatology, and Digestive Oncology, CUB Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium
,
G Costamagna
3   Fondazione Policlinico Universitario Agostino Gemelli, Digestive Endoscopy Unit, Rome, Italy
4   Centre for Endoscopic Research Therapeutics and Training (CERTT), Catholic University of Rome, Rome, Italy
› Author Affiliations
› Further Information
Also available at
 
 

    Aims The unprecedented situation caused by the COVID-19 pandemic has profoundly affected endoscopic practice in regard to access, volume, and workflow. We aimed to assess the potential changes in the technical outcomes of ERCP procedures carried out in patients with confirmed SARS-CoV-2 infection.

    Methods We conducted an international, multicenter, retrospective, matched case-control study of ERCP procedures carried out in patients with confirmed COVID-19. The main outcome was technical success of the procedure as assessed by the endoscopist, and the secondary outcome was the development of procedure-related adverse events. Each case was matched in a 1:4 ratio with controls extracted from each center’s database in order to identify relevant changes in outcome measures compared to the pre-pandemic era.

    Results Eighteen procedures performed in 16 COVID-19 patients (14 men, 65 years (9-82)) between the 15th of March and the 1st of July 2020 and 67 matched controls were included in the final analysis. Technical success was achieved in 14/18 procedures in COVID-19 cases, which was significantly lower as compared to the control group (14/18 vs. 64/67, p=0.034), with an endoscopic reintervention required in 9/18 cases. However, the rate of procedure-related adverse events was low in both groups (1/18 vs. 10/67, p=0.44). On multivariable analysis COVID-19 status remained the only risk factor for technical failure of the procedure (OR of 19.9 (95 %CI 1.4-269)).

    Table 1

    Comparison of technical characteristics and procedure-related outcomes between COVID-19 cases and the control group.

    COVID-19 cases

    Control cases

    p-value

    Cannulation method

    GW

    11/18

    47/67

    0.22

    CG

    DGW

    3/18

    4/18

    7/67

    5/67

    DGW

    4/18

    5/67

    Precut

    0/18

    7/67

    Other

    0/18

    1/67

    Failed

    0/18

    0/67

    Technical success

    14/18

    64/67

    0.034*

    Need for reintervention

    9/18

    20/67

    0.16

    Procedure-related AE

    1/18

    10/67

    0.44

    Conclusions The COVID-19 pandemic has affected the volume and practice of ERCP, without significantly impacting patient-related outcomes. Prioritizing cases and following recommendations on safety measures can ensure good outcome with minimal risk in dedicated centers.

    Citation Voiosu T, Voiosu A, Boškoski I et al. eP361 TECHNICAL OUTCOMES OF ERCP PROCEDURES IN PATIENTS WITH COVID-19. Endoscopy 2021; 53: S214.


    #

    Publication History

    Article published online:
    19 March 2021

    © 2021. European Society of Gastrointestinal Endoscopy. All rights reserved.

    Georg Thieme Verlag KG
    Rüdigerstraße 14, 70469 Stuttgart, Germany