Endoscopic Ultrasound (EUS) Elastography And Contrast Enhanced Eus For Discrimination Of Pancreatic Masses

Aims Investigate the clinical utility of contrast-enhanced endoscopic ultrasound (CEEUS) and endoscopic ultrasound elastography (EUS-E) in diagnosis of pancreatic masses.

Methods 30 patients with solid pancreatic focal lesions were included. All patients were subjected to laboratory investigations, conventional ultrasound, triphasic computed tomography (CT) scan, EUS-E, CEEUS, and EUS FNA. Diagnostic accuracy of EUS-E and CEEUS were compared and correlated to the pathology for pancreatic lesions.

Results Malignant lesions were larger in size (32.2 ± 10.3), and had greater SR-E-EUS and more hypovascular pattern. The mean strain ratio was 16.4 ± 8.14 for benign and 67.76 ± 72.45 for malignant lesions (P = 0.001). Hypovascular pattern after contrast injection was present in 76 % of malignant and 60 % of benign lesions (P = 0.66). ROC analysis for the mean SR-E-EUS of the region of interest yielded an optimal cutoff of 74.4 with an AUC of 0.91 (95 % CI: 0.74-0.98) for the best power distinction for malignancy. It provided a sensitivity and specificity of 75 % and 80 %, respectively.

Conclusions EUS based novel modalities (CE-EUS and EUS-E) could distinguish between benign and malignant lesions and improve the identification of the vascular pattern respectively. Both techniques could be considered a complementary imaging modality in the characterization of pancreatic tumors.

Citation Taleb A, Abd El-Rahim A, Abdel-Fattah A et al. eP412 ENDOSCOPIC ULTRASOUND (EUS) ELASTOGRAPHY AND CONTRAST ENHANCED EUS FOR DISCRIMINATION OF PANCREATIC MASSES. Endoscopy 2021; 53: S231.

Publication History

Article published online:
19 March 2021