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Horm Metab Res 1971; 3(4): 229-232
DOI: 10.1055/s-0028-1094159
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© Georg Thieme Verlag KG Stuttgart · New York

Preparation of Human C-Peptide

J.  Markussen1 , F.  Sundby1 , D. G. Smyth2 , A.  Ko2
  • 1Novo Research Institute, Copenhagen, Denmark
  • 2National Institute for Medical Research, London, England
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Publikationsdatum:
07. Januar 2009 (online)

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Abstract

Human C-peptide, which is the proinsulin connecting peptide minus the two terminal basic dipeptides, was isolated from human pancreas using a side fraction from the preparation of human insulin. Electrophoresis and amino acid sequence studies strongly indicate that the product is human C-peptide because of its similarity to porcine and bovine C-peptides.

Key words

C-Peptide - Proinsulin - Human Pancreas - Preparation of C-Peptide

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